A Case of Opioid Overdose and Subsequent Death After Medically Supervised Withdrawal: The Problematic Role of Rapid Tapers for Opioid Use Disorder

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dc.contributor.author Chang, Derek
dc.contributor.author Klimas, Jan
dc.contributor.author Wood, Evan
dc.contributor.author Fairbairn, Nadia
dc.date.accessioned 2018-05-21T12:11:54Z
dc.date.copyright 2018 Wolters Kluwer en
dc.date.issued 2018-01
dc.identifier.citation Journal of Addiction Medicine en
dc.identifier.uri http://hdl.handle.net/10197/9397
dc.description.abstract BACKGROUND: Relapse to opioid use is common after rapid opioid withdrawal. As a result, short-term tapers of opioid agonist/partial agonist medications, such as methadone and buprenorphine/naloxone, are no longer recommended by recent clinical care guidelines for the management of opioid use disorder. Nonetheless, rapid tapers are still commonplace in medically supervised withdrawal settings.CASE SUMMARY: We report a case of an individual with opioid use disorder who was prescribed a rapid buprenorphine/naloxone taper in a medically supervised withdrawal facility and who had a subsequent opioid overdose and death after discharge. DISCUSSION:The fatal outcome in this case study underscores the potential severe harms associated with use of rapid tapers. Given the increased overdose risk, tapers should be avoided and continuing care strategies, such as maintenance pharmacotherapy, should be initiated in medically supervised withdrawal settings. en
dc.description.sponsorship European Commission en
dc.description.sponsorship Irish Research Council en
dc.language.iso en en
dc.publisher Wolters Klumer en
dc.subject Addiction en
dc.subject Detoxification en
dc.subject Buprenorphine en
dc.subject Overdose en
dc.subject Opioid agoinist therapy en
dc.subject Taper en
dc.title A Case of Opioid Overdose and Subsequent Death After Medically Supervised Withdrawal: The Problematic Role of Rapid Tapers for Opioid Use Disorder en
dc.title.alternative A case of fatal overdose following inpatient detoxification: The problematic role of rapid opioid agonist tapers for opioid use disorder en
dc.type Journal Article en
dc.internal.authorcontactother jan.klimas@ucd.ie
dc.status Peer reviewed en
dc.identifier.volume 12 en
dc.identifier.issue 1 en
dc.identifier.startpage 80 en
dc.identifier.endpage 83 en
dc.check.date 2018-07-23
dc.identifier.doi 10.1097/ADM.0000000000000359
dc.neeo.contributor Chang|Derek|aut|
dc.neeo.contributor Klimas|Jan|aut|
dc.neeo.contributor Wood|Evan|aut|
dc.neeo.contributor Fairbairn|Nadia|aut|
dc.date.embargo 2019-01-31
dc.description.othersponsorship US National Institutes of Health en
dc.description.othersponsorship Canada Research Chairs en
dc.internal.rmsid 814635815
dc.date.updated 2017-10-03T17:46:41Z
 Access to this item has been restricted by the copyright holder until: 2019-01-31

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