Role of Genomics and RNA-seq in Studies of Fungal Virulence

DSpace/Manakin Repository

Show simple item record

dc.contributor.author Riccombeni, Alessandro
dc.contributor.author Butler, Geraldine
dc.date.accessioned 2012-10-15T16:10:49Z
dc.date.available 2013-12-31T04:00:07Z
dc.date.copyright 2012 Springer Science+Business Media en
dc.date.issued 2012-12
dc.identifier.citation Current Fungal Infection Reports en
dc.identifier.uri http://hdl.handle.net/10197/3865
dc.description.abstract Since its introduction in the last decade, massive parallel sequencing, or “next-generation sequencing”, has revolutionized our access to genomic information, providing accurate data with increasingly higher yields and lower costs with respect to first-generation technology. Massive parallel sequencing of cDNA, or RNA-seq, is progressively replacing array-based technology as the method of choice for transcriptomics. This review describes some of the most recent applications of next-generation sequencing technology to the study of pathogenic fungi, including Candida, Aspergillus and Cryptococcus species. Several integrated approaches illustrate the power and accuracy of RNA-seq for studying the biology of human fungal pathogens. In addition, the lack of consistency in data analysis is discussed. en
dc.language.iso en en
dc.publisher Springer en
dc.rights The final publication is available at springerlink.com en
dc.subject Aspergillus en
dc.subject Bioinformatics en
dc.subject Candida en
dc.subject ChIP-seq en
dc.subject Cryptococcus en
dc.subject Dermatophytes en
dc.subject Genomics en
dc.subject Next-generation sequencing en
dc.subject RNA-seq en
dc.subject.lcsh Aspergillus en
dc.subject.lcsh Bioinformatics en
dc.subject.lcsh Candida en
dc.subject.lcsh Nucleotide sequence en
dc.subject.lcsh Genomics en
dc.subject.lcsh Cryptococcus en
dc.title Role of Genomics and RNA-seq in Studies of Fungal Virulence en
dc.type Journal Article en
dc.internal.authorcontactother gbutler@ucd.ie
dc.internal.availability Full text available en
dc.status Not peer reviewed en
dc.identifier.volume 6 en
dc.identifier.issue 4
dc.identifier.startpage 297
dc.identifier.endpage 274
dc.identifier.doi 10.1007/s12281-012-0104-z
dc.neeo.contributor Riccombeni|Alessandro|aut|
dc.neeo.contributor Butler|Geraldine|aut|
dc.description.admin Author has checked copyright en
dc.description.admin DG - 10/10/2012 en
dc.description.admin Item not published yet and only available online as part of "Online First" feature. I'm not sure when it's due to published so i've set the check date to Jan 2013. Also, there is a 12 month publishing embargo - DG 10/10/12 en
dc.internal.rmsid 308472214
dc.date.updated 2012-10-02T10:56:42Z


Files in this item

This item appears in the following Collection(s)

Show simple item record

This item is available under the Attribution-NonCommercial-NoDerivs 3.0 Ireland. No item may be reproduced for commercial purposes. For other possible restrictions on use please refer to the publisher's URL where this is made available, or to notes contained in the item itself. Other terms may apply.

If you are a publisher or author and have copyright concerns for any item, please email research.repository@ucd.ie and the item will be withdrawn immediately. The author or person responsible for depositing the article will be contacted within one business day.

Search Research Repository


Advanced Search

Browse