Precursor-directed biosynthesis of fluorinated iturin A in Bacillus spp.

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dc.contributor.author Moran, Stephen
dc.contributor.author Rai, Dilip K.
dc.contributor.author Clark, Benjamin R.
dc.contributor.author Murphy, Cormac D.
dc.date.accessioned 2012-06-26T14:09:16Z
dc.date.available 2012-06-26T14:09:16Z
dc.date.copyright 2009 the authors en
dc.date.issued 2009
dc.identifier.citation Organic and Biomolecular Chemistry en
dc.identifier.uri http://hdl.handle.net/10197/3700
dc.description.abstract Some iturin A-producing strains of Bacillus subtilis will elaborate the novel fluorinated analogue when incubated with 3-fluoro-L-tyrosine. The activity of iturin A is dependent on the D-tyrosine residue and the presence of fluorotyrosine may result in an improvement of the biological properties of this lipopeptide. The fluorinated iturin might also be used as a probe for studying its interaction with biological membranes. en
dc.description.sponsorship Irish Research Council for Science, Engineering and Technology en
dc.format.extent 130292 bytes
dc.format.extent 33468 bytes
dc.format.extent 67072 bytes
dc.format.mimetype application/pdf
dc.format.mimetype application/pdf
dc.format.mimetype application/msword
dc.language.iso en en
dc.publisher RSC Publishing en
dc.relation.requires CSCB Research Collection en
dc.subject Fluorine en
dc.subject Antibiotic en
dc.subject.lcsh Fluorine en
dc.subject.lcsh Antibiotics--Synthesis en
dc.subject.lcsh Bacillus subtilis en
dc.title Precursor-directed biosynthesis of fluorinated iturin A in Bacillus spp. en
dc.type Journal Article en
dc.internal.availability Full text available en
dc.status Peer reviewed en
dc.identifier.volume 7 en
dc.identifier.issue 4 en
dc.identifier.startpage 644 en
dc.identifier.endpage 646 en
dc.identifier.doi 10.1039/b816345f
dc.neeo.contributor Moran|Stephen|aut| en
dc.neeo.contributor Rai|Dilip K.|aut| en
dc.neeo.contributor Clark|Benjamin R.|aut| en
dc.neeo.contributor Murphy|Cormac D.|aut| en
dc.description.admin au, ti - kpw22/6/12 en


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