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| dc.contributor.author | Shapero, Kayle | |
| dc.contributor.author | Fenaroli, Federico | |
| dc.contributor.author | Lynch, Iseult | |
| dc.contributor.author | Cottell, David C. | |
| dc.contributor.author | Salvati, Anna | |
| dc.contributor.author | Dawson, Kenneth A. | |
| dc.date.accessioned | 2012-06-21T15:38:42Z | |
| dc.date.available | 2012-06-21T15:38:42Z | |
| dc.date.copyright | The Royal Society of Chemistry 2011 | en |
| dc.date.issued | 2011 | |
| dc.identifier.citation | Molecular Biosystems | en |
| dc.identifier.uri | http://hdl.handle.net/10197/3694 | |
| dc.description.abstract | A spatio-temporal mapping of the uptake of silica (SiO2) nanoparticles of different sizes by lung epithelial cells has been obtained. Based on high control of nanoparticle dispersion in cell media and cell exposure, one obtains reproducible and quantitative time-resolved data using a combination of flow cytometry, fluorescence and electron microscopies. We are thereby able to give a rather detailed account of the journey of SiO2 nanoparticles from the early events of uptake to their final sub-cellular localization. | en |
| dc.description.sponsorship | Science Foundation Ireland | en |
| dc.description.sponsorship | Irish Research Council for Science, Engineering and Technology | en |
| dc.description.sponsorship | European Research Council | en |
| dc.format.extent | 1398564 bytes | |
| dc.format.extent | 1584805 bytes | |
| dc.format.mimetype | application/pdf | |
| dc.format.mimetype | application/pdf | |
| dc.language.iso | en | en |
| dc.publisher | Royal Society of Chemistry | en |
| dc.subject | Silica | en |
| dc.subject | Nanoparticle uptake | en |
| dc.subject | Flow cytometry | en |
| dc.subject | Transmission electronmicroscopy | en |
| dc.subject.lcsh | Silica | en |
| dc.subject.lcsh | Nanoparticles | en |
| dc.subject.lcsh | Flow cytometry | en |
| dc.subject.lcsh | Transmission electron microscopy | en |
| dc.title | Time and Space Resolved Uptake Study of Silica Nanoparticles by Human Cells | en |
| dc.type | Journal Article | en |
| dc.internal.availability | Full text available | en |
| dc.status | Peer reviewed | en |
| dc.identifier.volume | 7 | en |
| dc.identifier.issue | 2 | en |
| dc.identifier.startpage | 371 | en |
| dc.identifier.endpage | 378 | en |
| dc.identifier.doi | 10.1039/C0MB00109K | |
| dc.neeo.contributor | Shapero|Kayle|aut| | en |
| dc.neeo.contributor | Fenaroli|Federico|aut| | en |
| dc.neeo.contributor | Lynch|Iseult|aut| | en |
| dc.neeo.contributor | Cottell|David C.|aut| | en |
| dc.neeo.contributor | Salvati|Anna|aut| | en |
| dc.neeo.contributor | Dawson|Kenneth A.|aut| | en |
| dc.description.othersponsorship | EPA | en |
| dc.description.admin | 12M embargo has expired - 24/01/2012 AV | en |
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