Browsing College of Health Sciences by Subject "Protein-protein interactions"

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Prediction of short linear protein binding regions

Mooney, Catherine ; Pollastri, Gianluca ; Shields, Denis C. ; Haslam, Niall J. (Elsevier, 2012-01-06)

Short linear motifs in proteins (typically 3–12 residues in length) play key roles in protein–protein interactions by frequently binding specifically to peptide binding domains within interacting proteins. Their tendency ...
Profile-based short linear protein motif discovery

Haslam, Niall J. ; Shields, Denis C. (BioMed Central Ltd, 2012-05-18)

Background: Short linear protein motifs are attracting increasing attention as functionally independent sites, typically 3-10 amino acids in length that are enriched in disordered regions of proteins. Multiple methods have ...
Profile-based short linear protein motif discovery.

Haslam, Niall J. ; Shields, Denis C. (BioMed Central, 2012-05-18)

Background Short linear protein motifs are attracting increasing attention as functionally independent sites, typically 3-10 amino acids in length that are enriched in disordered regions of proteins. Multiple methods ...
SLiMSearch 2.0 : biological context for short linear motifs in proteins

Davey, Norman E. ; Haslam, Niall J. ; Shields, Denis C. ; Edwards, Richard J. (Oxford University Press, 2011-05-26)

Short, linear motifs (SLiMs) play a critical role in many biological processes. The SLiMSearch 2.0 (Short, Linear Motif Search) web server allows researchers to identify occurrences of a user-defined SLiM in a proteome, ...