Browsing Irish Drug Delivery Network Research Collection by Subject "Sodium caprate"

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Restoration of rat colonic epithelium after in situ intestinal instillation of the absorption promoter, sodium caprate

Wang, Xuexuan ; Maher, Sam ; Brayden, David James (Future Science, 2010-07)

Sodium caprate (C10) is an oral absorption promoter that is currently in clinical trials as a component of solid dosage forms for poorly permeable small molecules and peptides. Clinical data with zoledronic acid tablets ...
Safety and efficacy of sodium caprate in promoting oral drug absorption : from in vitro to the clinic

Maher, Sam ; Leonard, Thomas W ; Jacobson, Jette ; Brayden, David James (Elsevier, 2009-12-17)

A major challenge in oral drug delivery is the development of novel dosage forms to promote absorption of poorly permeable Class III drugs across the intestinal epithelium. To date, no absorption promoter has been approved ...