Browsing CSCB Research Collection by Author "Clark, Benjamin R."

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Biosynthesis of pyrrolylpolyenes in Auxarthron umbrinum

Clark, Benjamin R. ; Murphy, Cormac D. (RSC Publishing, 2009)

The biosynthesis of the pyrrolylpolyene rumbrin (1) in the fungus Auxarthron umbrinum was elucidated using feeding studies with labelled precursors. Incorporation of stable isotopes from [15N]-proline, [13C]-methionine and ...
Precursor-directed biosynthesis of fluorinated iturin A in Bacillus spp.

Moran, Stephen ; Rai, Dilip K. ; Clark, Benjamin R. ; Murphy, Cormac D. (RSC Publishing, 2009)

Some iturin A-producing strains of Bacillus subtilis will elaborate the novel fluorinated analogue when incubated with 3-fluoro-L-tyrosine. The activity of iturin A is dependent on the D-tyrosine residue and the presence ...