Browsing Conway Institute Research Collection by Author "Turner, Elizebeth C."

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Browsing Conway Institute Research Collection by Author "Turner, Elizebeth C."

Now showing items 1-5 of 5

Estrogen increases expression of the human prostacyclin receptor within the vasculature through an ERα-dependent mechanism

Turner, Elizebeth C. ; Kinsella, B. Therese (Elsevier, 2010-02-26)

Prostacyclin and the prostacyclin receptor (IP) are implicated in mediating many of the atheroprotective effects of estrogen in both humans and in animal models but through unknown mechanisms. Hence, herein the influence ...
Identification of an interaction between the TPalpha and TPbeta isoforms of the human thromboxane A2 receptor with protein kinase C-related kinase (PRK) 1 : implications for prostate cancer.

Turner, Elizebeth C. ; Kavanagh, David J. ; Mulvaney, Eamon P. ; McLean, Caitriona ; Wikström, Katarina ; Reid, Helen M. ; Kinsella, B. Therese (American Society for Biochemistry and Molecular Biology, 2011-04-29)

In humans, thromboxane (TX)A2 signals through the TPalpha and TPbeta isoforms of the TXA2 receptor, or TP. Herein, the RhoA effector protein kinase C-related kinase (PRK) 1 was identified as an interactant of both TPalpha ...
Interaction of the human prostacyclin receptor with the PDZ adapter protein PDZK : role in endothelial cell migration and angiogenesis

Turner, Elizebeth C. ; Mulvaney, Eamon P. ; Reid, Helen M. ; Kinsella, B. Therese (American Society for Cell Biology, 2011-06-08)

Prostacyclin is increasingly implicated in re-endothelialization and angiogenesis but through largely unknown mechanisms. Herein, the HDL scavenger receptor class B, type 1 (SR-B1) adapter protein PDZ domain-containing ...
Regulated expression of the α isoform of the human thromboxane A2 receptor during megakaryocyte differentiation : a coordinated role for WT1, Egr1 & Sp1

Gannon, AnneMarie ; Turner, Elizebeth C. ; Reid, Helen M. ; Kinsella, B. Therese (Elsevier, 2009-11-20)

Thromboxane plays an essential role in haemostasis, regulating platelet aggregation and vessel tone. In humans, it signals through the TPalpha and TPbeta isoforms that are transcriptionally regulated by distinct promoters, ...
Transcriptional regulation of the human prostacyclin receptor gene is dependent on Sp1, PU.1 and Oct-1 in megakaryocytes and endothelial cells

Turner, Elizebeth C. ; Kinsella, B. Therese (Elsevier, 2009-02-27)

Prostacyclin plays a central role in haemostasis, inflammation and nociception. However, the factors regulating expression of the prostacyclin receptor (IP) gene in humans, or in other species, have not been identified. ...

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Browsing Conway Institute Research Collection by Author "Turner, Elizebeth C."

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