Browsing Conway Institute Research Collection by Subject "Desensitisation"

DSpace/Manakin Repository

Now showing items 1-2 of 2

Prostaglandin D2 receptor-mediated desensitization of the alpha isoform of the human thromboxane A2 receptor

Foley, John F. ; Kelley-Hickie, Leanne P. ; Kinsella, B. Therese (Elsevier, 2001-07-15)

Thromboxane (TX) A2 and prostaglandin (PG) D2 mediate opposing actions in platelets and in vascular and non-vascular smooth muscle. Here, we investigated the effects of stimulation of the PGD2 receptor (DP) on signaling ...
Thromboxane A2 signalling in humans : a ‘tail’ of two receptors

Kinsella, B. Therese (Portland Press, 2001)

Since its discovery in 1975, we now have a wealth of knowledge relating to the biochemical, pharmacological and physiologic actions of thromboxane (TX) A2 and its related metabolites. These molecular insights have been ...