Browsing Conway Institute by Subject "HMGB-1"

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High-mobility group box protein 1: a novel mediator of inflammatory-induced renal epithelial-mesenchymal transition

Lynch, Julie ; Nolan, Stephen ; Slattery, Craig ; Feighery, Ronan ; Ryan, Michael P. ; McMorrow, Tara (Karger, 2010-11-24)

Background: High mobility group box protein 1 (HMGB-1) is a chromatin binding protein that bends DNA thereby facilitating gene transcription. HMGB-1 has also been observed as an extracellular secreted protein in serum of ...

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