Browsing Biomolecular and Biomedical Science Research Collection by Subject "Megakaryocytes"

DSpace/Manakin Repository

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Regulated expression of the α isoform of the human thromboxane A2 receptor during megakaryocyte differentiation : a coordinated role for WT1, Egr1 & Sp1

Gannon, AnneMarie ; Turner, Elizebeth C. ; Reid, Helen M. ; Kinsella, B. Therese (Elsevier, 2009-11-20)

Thromboxane plays an essential role in haemostasis, regulating platelet aggregation and vessel tone. In humans, it signals through the TPalpha and TPbeta isoforms that are transcriptionally regulated by distinct promoters, ...
Regulation of the human prostacyclin receptor gene in megakaryocytes : major roles for C/EBPδ and PU.1

Keating, Garret L. ; Turner, Elizebeth C. ; Kinsella, B. Therese (Elsevier, 2012-05)

The prostanoid prostacyclin plays a central role in haemostasis and vascular repair. Recent studies investigating the regulation of the human prostacyclin receptor (hIP) gene identified an upstream repressor region (URR) ...

Now showing items 1-2 of 2