Browsing School of Biomolecular & Biomedical Science by Subject "F-19 NMR"

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Bacterial production of hydroxylated and amidated metabolites of flurbiprofen

Bright, Tara V. ; Clark, Benjamin R. ; O'Brien, Eimear ; Murphy, Cormac D. (Elsevier, 2011-11)

Several Streptomyces and Bacillus strains were examined for their ability to transform the anti-inflammatory drug flurbiprofen 1 to the hydroxylated metabolites that are found in humans after ingestion of this compound. ...
Biotransformation of fluorobiphenyl by Cunninghamella elegans

Amadio, Jessica ; Murphy, Cormac D. (Springer, 2010)

The fungus Cunninghamella elegans is a useful model of human catabolism of xenobiotics. In this paper, the biotransformation of fluorinated biphenyls by C. elegans was investigated by analysis of the culture supernatants ...