Browsing School of Biomolecular & Biomedical Science by Author "Donnelly, Clár"

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Bacterial defluorination of 4-fluoroglutamic acid

Donnelly, Clár ; Murphy, Cormac D. (Springer, 2007)

Fluorinated amino acids are used as enzyme inhibitors, mechanistic probes and in the production of pharmacologically active peptides. Because enantiomerically pure 4-fluoroglutamate is difficult to prepare, the selective ...
Purification and properties of fluoroacetate dehalogenase from Pseudomonas fluorescens DSM 8341

Donnelly, Clár ; Murphy, Cormac D. (Springer, 2009)

The degradation of fluoroacetate by microorganisms has been established for some time, although only a handful of dehalogenases capable of hydrolyzing the stable C-F bond have been studied. The bacterium Pseudomonas ...