Browsing School of Biomolecular & Biomedical Science by Author "Cassidy, Hilary"

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Identification of β2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods

Johnston, Olwyn ; Cassidy, Hilary ; O'Connell, Séin ; O'Riordan, Aisling ; Gallagher, William ; Maguire, Patricia B. ; Wynne, Kieran ; Cagney, Gerard ; Ryan, Michael P. ; Conlon, Peter J. ; McMorrow, Tara (Wiley, 2011-08)

Chronic allograft nephropathy (CAN) remains the leading cause of renal graft loss after the first year following renal transplantation. This study aimed to identify novel urinary proteomic profiles, which could distinguish ...
Mechanisms of calcineurin inhibitor nephrotoxicity in chronic allograft injury

Slattery, Craig ; Cassidy, Hilary ; Johnston, Olwyn ; Ryan, Michael P. ; McMorrow, Tara (Intech, 2012)

The first successful transplantation of a human kidney was performed more than 50 years ago by Murray and colleagues in 1954 between identical twins. The success of this transplantation was due to the fact that no significant ...
The Role of MAPK in Drug-Induced Kidney Injury

Cassidy, Hilary ; Radford, Robert ; Slyne, Jennifer ; O'Connell, Sein ; Slattery, Craig ; Ryan, Michael P. ; McMorrow, Tara (Hindawi Publishers, 2012)

This paper focuses on the role that mitogen-activated protein kinases (MAPKs) play in drug-induced kidney injury. The MAPKs, of which there are four major classes (ERK, p38, JNK, and ERK5/BMK), are signalling cascades ...

Now showing items 1-3 of 3