Poly(2-(dimethylamino ethyl)methacrylate) (pDMAEMA) is a cationic polymer with potential as an antimicrobial agent and as a non-viral gene delivery vector. The aim was to further elucidate the cytotoxicity of a selected ...
Antimicrobial peptides (AMPs) are naturally occurring entities with potential as pharmaceutical candidates
and/or food additives. They are present in many organisms including bacteria, insects, fish and
mammals. While ...
The use of higher-order functions, as a method of abstraction and re-use in EC encodings, has been the subject of relatively little research. In this paper we introduce and give motivation for the ideas of higher-order ...
Background: High mobility group box protein 1 (HMGB-1) is a chromatin binding protein that bends DNA thereby facilitating gene transcription. HMGB-1 has also been observed as an extracellular secreted protein in serum of ...
A new development on treatment wetland technology for the purpose of achieving high rate nitrogen removal from high strength wastewater has been made in this study. The laboratory scale alum sludge-based intermittent ...
Thromboxane (TX) A2 is a potent stimulator of platelet activation/aggregation and smooth muscle contraction and contributes to a variety of pathologies within the vasculature. In this study, we investigated the mechanism ...
This article uses Donald Horowitz’s theory of ethnic party competition in order to understand the development of the Northern Ireland Social Democratic and Labour Party (SDLP) during the first decade of its existence. The ...
The aim of this paper is to analyse the characteristics of Irish households that have a member participating in higher education, using surveys of Irish households collected in 1994-95 and 1999-2000. The results do not ...
This paper investigates the risk-return relationship in determination of housing asset pricing. In so doing, the paper evaluates behavioral hypotheses advanced by Case and Shiller (1988, 2002, 2009) in studies of boom and ...
This paper investigates the risk-return relationship in determination of housing asset
pricing. In so doing, the paper evaluates behavioral hypotheses advanced by Case and
Shiller (1988, 2002, 2009) in studies of boom ...
This paper incorporates the stylised fact of labour market rationing into an analysis of marginal tax reform in Ireland. In the absence of weak separability between goods and leisure, labour market rationing will have both ...
The non take-up of social assistance benefits due to claim costs may seriously limit the anti-poverty effect of these programs. Yet, available evidence is fragmented and mostly relies on interview-based data, potentially ...
This paper explores the vital role played by the Social Democratic and Labour Party (SDLP) in the formulation of a new political discourse and conceptual approach to the Northern Ireland problem. In particular, it shows ...
This paper describes the use of the SoSAA software framework to implement the hybrid management of communication channels (backchannels) across a distributed software system. SoSAA is a new integrated
architectural solution ...
The Water Framework Directive has been the catalyst for a considerable amount of data collection, analysis and research covering a wide range of physical and biological characteristics and involving a wide range of scientific, ...
This paper extends the widely used ordered choice model by introducing stochastic
thresholds and interval-specific outcomes. The model can be interpreted as a generalization of the GAFT (MPH) framework for discrete duration ...
In humans, thromboxane (TX)A2 signals through the TPalpha and TPbeta isoforms of the TXA2 receptor, or TP. Herein, the RhoA effector protein kinase C-related kinase (PRK) 1 was identified as an interactant of both TPalpha ...
The human prostacyclin receptor (hIP) undergoes agonist-dependent trafficking involving a direct interaction with Rab11a GTPase. The region of interaction was localised to a 14 residue Rab11a binding domain (RBD) within ...
The calcineurin inhibitor cyclosporine A (CsA) is a widely used immunosuppressive agent. However,nephrotoxicity is a serious side effect observed in patients which limits clinical use of CsA. CsA nephrotoxicity is associated ...