This study evolves and categorises a population of conceptual designs by their ability to handle physical constraints. The design process involves a trade-off between form and function. The aesthetic considerations of the ...
Over the last years, the effects of neutrality have attracted the attention of many researchers in the Evolutionary Algorithms (EAs) community. A mutation from one gene to another is considered as neutral if this modification ...
We investigate the effects of semantically-based crossover operators in Genetic Programming, applied to real-valued symbolic regression problems. We propose two new relations derived from the semantic distance between ...
This paper examines how the semantic locality of a search operator affects the fitness landscape of Genetic Programming (GP). We compare the fitness landscapes of GP search when standard subtree mutation and a recently ...
This paper investigates the effects of early stopping as a method to counteract overfitting in evolutionary data modelling using Genetic Programming. Early stopping has been proposed as a method to avoid model overtraining, ...
There have been many approaches to modularity in the field of evolutionary computation, each tailored to function with a particular representation. This research examines one approach to modularity and grammar modification ...
Chronic allograft nephropathy (CAN) remains the leading cause of renal graft loss after the first year following renal transplantation. This study aimed to identify novel urinary proteomic profiles, which could distinguish ...
The calcineurin inhibitor cyclosporine A (CsA) is a widely used immunosuppressive agent. However,nephrotoxicity is a serious side effect observed in patients which limits clinical use of CsA. CsA nephrotoxicity is associated ...
The human prostacyclin receptor (hIP) undergoes agonist-dependent trafficking involving a direct interaction with Rab11a GTPase. The region of interaction was localised to a 14 residue Rab11a binding domain (RBD) within ...
The past decade has witnessed a steady growth of open source software usage in industry and academia, leading to a complex ecosystem of projects. Web and subsequently geographical information systems have become prominent ...