Browsing College of Science by Subject "Receptors, Prostaglandin"

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Prostaglandin D2 receptor-mediated desensitization of the alpha isoform of the human thromboxane A2 receptor

Foley, John F. ; Kelley-Hickie, Leanne P. ; Kinsella, B. Therese (Elsevier, 2001-07-15)

Thromboxane (TX) A2 and prostaglandin (PG) D2 mediate opposing actions in platelets and in vascular and non-vascular smooth muscle. Here, we investigated the effects of stimulation of the PGD2 receptor (DP) on signaling ...
Recycling of the human prostacyclin receptor is regulated through a direct interaction with Rab11a GTPase

Wikström, Katarina ; Reid, Helen M. ; Hill, Maria ; English, Karol A. ; O'Keeffe, Martina B. ; Kimbembe, Cisca C. ; Kinsella, B. Therese (Elsevier, 2008-12)

The human prostacyclin receptor (hIP) undergoes agonist-induced internalization but the mechanisms regulating its intracellular trafficking and/or recycling to the plasma membrane are poorly understood. Herein, we conducted ...

Now showing items 1-2 of 2