Browsing College of Science by Subject "Receptor"

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Expression and tissue distribution of the mRNAs encoding the human thromboxane A2 receptor (TP) alpha and beta isoforms

Miggin, Sinead M. ; Kinsella, B. Therese (Elsevier, 1998-11-27)

The human (h) TXA2 receptor (TP), a G protein-coupled receptor, exists as two isoforms, TPalpha and TPbeta, which arise by alternative mRNA splicing and differ exclusively in their carboxyl terminal cytoplasmic regions. ...
Interaction of angio-associated migratory cell protein with the TPα and TPβ isoforms of the human thromboxane A2 receptor

Reid, Helen M. ; Wikström, Katarina ; Kavanagh, David J. ; Mulvaney, Eamon P. ; Kinsella, B. Therese (Elsevier, 2011-04)

In humans, thromboxane (TX) A2 signals through the TPα and TPβ isoforms of its G-protein coupled TXA2 receptor (TP) to mediate a host of (patho)physiologic responses. Herein, angio-associated migratory cell protein (AAMP) ...
Thromboxane A2 signalling in humans : a ‘tail’ of two receptors

Kinsella, B. Therese (Portland Press, 2001)

Since its discovery in 1975, we now have a wealth of knowledge relating to the biochemical, pharmacological and physiologic actions of thromboxane (TX) A2 and its related metabolites. These molecular insights have been ...