Browsing College of Science by Subject "Kidneys--Diseases"

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Identification of β2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods

Johnston, Olwyn ; Cassidy, Hilary ; O'Connell, Séin ; O'Riordan, Aisling ; Gallagher, William ; Maguire, Patricia B. ; Wynne, Kieran ; Cagney, Gerard ; Ryan, Michael P. ; Conlon, Peter J. ; McMorrow, Tara (Wiley, 2011-08)

Chronic allograft nephropathy (CAN) remains the leading cause of renal graft loss after the first year following renal transplantation. This study aimed to identify novel urinary proteomic profiles, which could distinguish ...
The Role of MAPK in Drug-Induced Kidney Injury

Cassidy, Hilary ; Radford, Robert ; Slyne, Jennifer ; O'Connell, Sein ; Slattery, Craig ; Ryan, Michael P. ; McMorrow, Tara (Hindawi Publishers, 2012)

This paper focuses on the role that mitogen-activated protein kinases (MAPKs) play in drug-induced kidney injury. The MAPKs, of which there are four major classes (ERK, p38, JNK, and ERK5/BMK), are signalling cascades ...

Now showing items 1-2 of 2