Browsing College of Science by Subject "Gene Expression"

DSpace/Manakin Repository

Now showing items 1-3 of 3

Estrogen increases expression of the human prostacyclin receptor within the vasculature through an ERα-dependent mechanism

Turner, Elizebeth C. ; Kinsella, B. Therese (Elsevier, 2010-02-26)

Prostacyclin and the prostacyclin receptor (IP) are implicated in mediating many of the atheroprotective effects of estrogen in both humans and in animal models but through unknown mechanisms. Hence, herein the influence ...
Expression and tissue distribution of the mRNAs encoding the human thromboxane A2 receptor (TP) alpha and beta isoforms

Miggin, Sinead M. ; Kinsella, B. Therese (Elsevier, 1998-11-27)

The human (h) TXA2 receptor (TP), a G protein-coupled receptor, exists as two isoforms, TPalpha and TPbeta, which arise by alternative mRNA splicing and differ exclusively in their carboxyl terminal cytoplasmic regions. ...
Transcriptional regulation of the human prostacyclin receptor gene is dependent on Sp1, PU.1 and Oct-1 in megakaryocytes and endothelial cells

Turner, Elizebeth C. ; Kinsella, B. Therese (Elsevier, 2009-02-27)

Prostacyclin plays a central role in haemostasis, inflammation and nociception. However, the factors regulating expression of the prostacyclin receptor (IP) gene in humans, or in other species, have not been identified. ...