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(Future Science, 2010-07)Sodium caprate (C10) is an oral absorption promoter that is currently in clinical trials as a component of solid dosage forms for poorly permeable small molecules and peptides. Clinical data with zoledronic acid tablets ...
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(Elsevier, 2010-08)Poly(2-(dimethylamino ethyl)methacrylate) (pDMAEMA) is a cationic polymer with potential as an antimicrobial agent and as a non-viral gene delivery vector. The aim was to further elucidate the cytotoxicity of a selected ...
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(University College Dublin. School of Economics, 2005-05)Past population dynamics in Africa have remained largely elusive due to the lack of demographic data. Researchers are understandably deterred from trying to explain what is not known and African historical population ...
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(University College Dublin. Institute for British-Irish Studies, 2010)This largely historiographical paper examines the initial inclusion of native Gaelic clergy in the plantation church in Ulster and their gradual disappearance over the course the next twenty-five years. This was a highly ...
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(Mary Ann Liebert, 2010-07-26)More than 85% of reported brain traumas are classified clinically as “mild” using GCS; qualitative MRI findings are scarce and provide little correspondence to clinical symptoms. Our goal, therefore, was to establish in-vivo ...
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(Elsevier, 2009-12-17)A major challenge in oral drug delivery is the development of novel dosage forms to promote absorption of poorly permeable Class III drugs across the intestinal epithelium. To date, no absorption promoter has been approved ...
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(Elsevier, 2011-01-20)Salmon calcitonin (sCT) was conjugated via cysteine-1 to novel comb-shaped end-functionalised (poly(PEG) methyl ether methacrylate) (sCT-P) polymers, to yield conjugates of total molecular weights (MW) inclusive of sCT: ...
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(Elsevier, 2013-01-05)The existence of opioid receptors in mammalian myometrial tissue is now widely accepted. Previously enkephalin degrading enzymes have been shown to be elevated in pregnant rat uterus and a met-enkephalin analogue has been ...
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(Elsevier, 2004-06)Almost since its inception, the concept of modernity was found to display tensions between its emancipatory potential to liberate the human subject from the manacles of tradition, and the application of reason to co-ordinate ...
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(Elsevier, 2012-09)In utero exposure of rodents to valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, has been proposed to induce an adult phenotype with behavioural characteristics reminiscent of those observed in autism spectrum ...
Now showing items 1-10 of 10