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(American Chemical Society, 2010-04-20)Accumulation of PrP(Sc), an insoluble and protease-resistant pathogenic isoform of the cellular prion protein (PrP(C)), is a hallmark in prion diseases. Branched polyamines, including PPI (poly(propylene imine)) dendrimers, ...
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(American Chemical Society, 2012-12-12)Prion diseases are characterized by the accumulation of PrP(Sc), an aberrantly folded isoform of the host protein PrP(C). Specific forms of synthetic molecules known as dendrimers are able to eliminate protease-resistant ...
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(Elsevier, 2009-08)The peptide-derived glyoxal inhibitor Z-Ala-Ala-Phe-glyoxal has been shown to be ~10 fold more effective as an inhibitor of subtilisin than Z-Ala-Pro-Phe-glyoxal. Signals at 107.2 p.p.m. and 200.5 p.p.m. are observed for ...
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(Academic Press (Elsevier), 2011-10)Programmed cell death (PCD) describes a small number of processes that result in a highly controlled, and organised, form of cellular destruction, activated in every part of the plant, throughout its entire life cycle. For ...
Now showing items 1-4 of 4