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Genetics of vesicoureteral reflux

Puri, Prem ; Gosemann, Jan-Hendrik ; Darlow, John ; Barton, David E. (Nature Publishing Group, 2011-10)

Primary vesicoureteral reflux (VUR) is the most common urological anomaly in children, affecting 1–2% of the pediatric population and 30–40% of children presenting with urinary tract infections (UTIs). Refluxassociated ...
Identification of β2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods

Johnston, Olwyn ; Cassidy, Hilary ; O'Connell, Séin ; O'Riordan, Aisling ; Gallagher, William ; Maguire, Patricia B. ; Wynne, Kieran ; Cagney, Gerard ; Ryan, Michael P. ; Conlon, Peter J. ; McMorrow, Tara (Wiley, 2011-08)

Chronic allograft nephropathy (CAN) remains the leading cause of renal graft loss after the first year following renal transplantation. This study aimed to identify novel urinary proteomic profiles, which could distinguish ...
Identification of novel indicators of cyclosporine A nephrotoxicity in a CD-1 mouse model

O'Connell, Séin ; Slattery, Craig ; Ryan, Michael P. ; McMorrow, Tara (Elsevier, 2011-04-15)

The calcineurin inhibitor cyclosporine A (CsA) is a widely used immunosuppressive agent. However,nephrotoxicity is a serious side effect observed in patients which limits clinical use of CsA. CsA nephrotoxicity is associated ...

Now showing items 1-3 of 3