Background: Prediction of protein structures from their sequences is still one of the open grand challenges of computational biology. Some approaches to protein structure prediction, especially ab initio ones, rely to some ...
A significant step towards establishing the structure and function of a protein is the prediction of the local conformation of the polypeptide chain. In this article, we present systems for the prediction of three new ...
The recent Environmental Noise Directive (END) of the European Union (EU) requires that noise maps and action plans are compiled for agglomerations with a population
greater than 250,000 individuals. This paper reports ...
This paper explores methodological issues surrounding the implementation of the EU Environmental Noise Directive (END) across Member States. It also highlights future policy implications arising from the analysis which ...
One of the key difficulties with urban environmental noise mapping is disseminating results from noise studies in a manner that is easily understood by the general public. Indeed, it is one of the requirements of the ...
Network modeling can be approached using either discriminative or probabilistic
models. In the task of link prediction a probabilistic model will give a probability
for the existence of a link; while in some scenarios ...
A mapping is local if it preserves neighbourhood. In Evolutionary Computation, locality is generally described as the property that neighbouring genotypes correspond to neighbouring phenotypes. A representation has high ...
Background: Proteins, especially larger ones, are often composed of individual evolutionary units, domains, which have their own function and structural fold. Predicting domains is an important intermediate step in protein ...
We describe Distill, a suite of servers for the prediction of protein structural
features: secondary structure; relative solvent accessibility; contact density; backbone structural motifs; residue contact maps at 6, 8 and ...
Analysis of the thermal regime created by a geothermal borehole heat exchanger is performed using a closed form radial heat flow equation, a geothermal borehole heat exchanger design tool and a finite element model. ...