Sodium caprate (C10) is an oral absorption promoter that is currently in clinical trials as a component of solid dosage forms for poorly permeable small molecules and peptides. Clinical data with zoledronic acid tablets ...
Background: High mobility group box protein 1 (HMGB-1) is a chromatin binding protein that bends DNA thereby facilitating gene transcription. HMGB-1 has also been observed as an extracellular secreted protein in serum of ...
Poly(2-(dimethylamino ethyl)methacrylate) (pDMAEMA) is a cationic polymer with potential as an antimicrobial agent and as a non-viral gene delivery vector. The aim was to further elucidate the cytotoxicity of a selected ...
This paper describes a procedure developed for the estimation of marginal damage costs for airfield pavements in order to establish off-peak airport charges at Irish airports. The Commission for Aviation
Regulation has ...
Advances in surface-applied corrosion inhibitors suggest that they have the potential to prevent or significantly retard corrosion of steel in reinforced concrete structures. It is thought that the effectiveness of the ...
Brick produced prior to the mid-twentieth century exhibit high levels of variability in appearance, geometry, and mechanical properties. Understanding historic brick variability is important for accurate performance ...
The corrosion of European concrete highway structures leads to traffic disruption, significant expenditure on remedial works and ultimately threatens to impact on European competitiveness. A potentially more efficient ...
A spatio-temporal mapping of the uptake of silica (SiO2) nanoparticles of different sizes by lung epithelial cells has been obtained. Based on high control of nanoparticle dispersion in cell media and cell exposure, one ...
Since the September 11, 2001 terrorist attacks in the United States (U.S.), there has been a marked increase in both public and private sector demand for increased blast-mitigation for existing buildings. To adequately ...
Building rehabilitation is critical for numerous older urban areas, many of which have inadequate foundations to support new demands. Consequently, development of practical methods to strengthen existing foundations is ...