Collections matching your query

• Irish Drug Delivery Network [6]
• Irish Drug Delivery Network Research Collection [6]

• Safety and efficacy of sodium caprate in promoting oral drug absorption : from in vitro to the clinic 

  Maher, Sam ; Leonard, Thomas W ; Jacobson, Jette ; Brayden, David James (Elsevier, 2009-12-17)

  A major challenge in oral drug delivery is the development of novel dosage forms to promote absorption of poorly permeable Class III drugs across the intestinal epithelium. To date, no absorption promoter has been approved ...
• Opportunities for drug-delivery research in nutraceuticals and functional foods? 

  Brayden, David James ; Baird, Alan W. (Future Science, 2013-03)
• Colonic absorption of salmon calcitonin using tetradecyl maltoside (TDM) as a permeation enhancer 

  Petersen, Signe Beck ; Nielsen, Lisette Gammelgaard ; Rahbek, Ulrik Lytt ; Guldbrandt, Mette ; Brayden, David James (Elsevier, 2013-03)

  Calcitonin is used as a second line treatment of postmenopausal osteoporosis, but widespread acceptance is somewhat limited by subcutaneous and intranasal routes of delivery. This study attempted to enable intestinal sCT ...
• Alcohol screening and brief intervention among drug users in primary care : a discussion paper 

  Field, Catherine Anne ; Klimas, Jan ; Barry, Joe ; Bury, Gerard ; Keenan, Eamon ; Lyons, Suzi ; Smyth, Bobby P. ; Cullen, Walter (Springer, 2012-06-01)

  Background problem alcohol use is common among problem drug users (PDU) and associated with adverse health outcomes. Primary care has an important role in the overall stepped approach to alcohol treatment, especially ...
• Restoration of rat colonic epithelium after in situ intestinal instillation of the absorption promoter, sodium caprate 

  Wang, Xuexuan ; Maher, Sam ; Brayden, David James (Future Science, 2010-07)

  Sodium caprate (C10) is an oral absorption promoter that is currently in clinical trials as a component of solid dosage forms for poorly permeable small molecules and peptides. Clinical data with zoledronic acid tablets ...
• Exploring healthcare professionals experience and attitudes towards screening for and treatment of problem alcohol use among drug users attending primary care 

  Field, Catherine Anne ; Klimas, Jan ; Barry, Joe ; Bury, Gerard ; Keenan, Eamon ; Lyons, Suzi ; Smyth, Bobby P. ; Cullen, Walter (2011-01-20)

  Problem alcohol use (PAU) is common among drug users (DUs) prevalence rates vary from 13-76%, in a recent Irish study of patients on methadone 35% had an AUDIT score indicating PAU. PAU is associated with adverse health ...
• Examination of cell-host-biomaterial interactions via high-throughput technologies : a re-appraisal 

  Power, Karen Ann ; Fitzgerald, Kathleen T. ; Gallagher, William M. (Elsevier, 2010-09)

  Biomaterials are required to act harmoniously when exposed to the body or bodily fluids. Investigating cellular or in vivo phenotypic responses and protein adsorption to the material surface helps to determine the associated ...
• Varying penetration ratios of wind turbine technologies for voltage and frequency stability 

  Vittal, Eknath ; Keane, Andrew ; O'Malley, Mark (IEEE, 2008-07)

  This paper examines the ability of a power system to accommodate wind generation with varying ratios of doubly fed induction generator and fixed speed induction generator turbines from both static and dynamic aspects. By ...