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(Wiley-Blackwell, 2012-01)Protein kinases (PK) control phosphorylation in eukaryotic cells, and thereby regulate metabolic pathways, cell cycle progression, apoptosis and transcription. Consequently there is significant interest in manipulating ...
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(Springer, 2013-02)Conformationally restricted amino acids are important components in peptidomimetics and drug design. Herein, we describe the synthesis of a novel, non-proteinogenic constrained delta amino acid containing a cyclobutane ...
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(Springer, 2013-01-01)The effect of various organic solvents on the catalytic activity, stability and substrate specificity of alchohol dehydrogenase from Haloferax volcanii (HvADH2) was evaluated. The HvADH2 showed remarkable stability and ...
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(University College Dublin. School of Economics, 2008-01)This paper shows that nonlinearity can provide an explanation for the forward exchange rate anomaly (Fama, 1984). Using sterling-Canadian dollar data, and modelling nonlinearity of unspecified form by means of a random ...
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(Cambridge University Press, 2004-07)Previous research has suggested that hidden income arising from home ownership has important consequences for poverty measurement as it tends to favour certain low income groups, especially the elderly, and to have a ...
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(IEEE, 2013-05-26)We show that Slepian’s Variant I permutation codes implement first-order perfect steganography (i.e., histogram-preserving steganography). We give theoretical expressions for the embedding distortion, embedding rate and ...
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(Ama American Medical Association, 2003-06)Objectives To describe patterns of care for primary open-angle glaucoma (POAG) and assess conformance with the American Academy of Ophthalmology's Preferred Practice Pattern (PPP). Methods We obtained administrative, ...
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(Taylor and Francis, 2009)The creative knowledge city has received considerable attention in the last number of years, not only in the academic literature but also from urban policy-makers. Much of the attention has centred on the ‘creative class’ ...
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(Mary Ann Liebert, 2006-10-24)A significant step towards establishing the structure and function of a protein is the prediction of the local conformation of the polypeptide chain. In this article, we present systems for the prediction of three new ...
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(Springer, 2005-08)Changes in collective categories of identity are at the core of social transformation. The causal linkages between identity change, institutional change and change in modes of practice are, however, complex. Developing and ...