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(Elsevier B.V., 2012-02)The chemical shift of the carboxylate carbon of Z-tryptophan is increased from 179.85 to 182.82 ppm and 182.87 on binding to thermolysin and stromelysin-1 respectively. The chemical shift of Z-phenylalanine is also increased ...
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(Elsevier, 2012-01-06)Short linear motifs in proteins (typically 3–12 residues in length) play key roles in protein–protein interactions by frequently binding specifically to peptide binding domains within interacting proteins. Their tendency ...
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(RSC Publishing, 2011)The quaternarized pdppz derivative 1 was shown to bind strongly to DNA with concomitant changes in its ground and excited state photophysical properties. Furthermore, the compound also showed rapid cellular uptake, and ...
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(American Society for Biochemistry and Molecular Biology, Inc., 2012-09-11)Prostacyclin and its prostacyclin receptor, the IP, play essential roles in regulating haemostasis and vascular tone and have also been implicated in a range cardio-protective effects, but through largely unknown mechanisms. ...
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(Wiley-VCH, 2012-01-09)Rhodium(III) complexes comprising monoanionic C,C,C-tridentate dicarbene ligands activate Si–H bonds and catalyse the hydrolysis of hydrosilanes to form silanols and siloxanes with concomitant release of H2. In dry MeNO2, ...
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(University College Dublin. School Of Economics, 2006-11)This paper extends Che and Gale (1998) by allowing the incumbent politician to have a preference for the policy position of one of the lobbyists. The effect of a contribution cap is analyzed where two lobbyists contest for ...
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(BioMed Central Ltd, 2012-05-18)Background: Short linear protein motifs are attracting increasing attention as functionally independent sites, typically 3-10 amino acids in length that are enriched in disordered regions of proteins. Multiple methods have ...
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(Taylor & Francis, 2012-01-16)A family of organic molecules containing the DNA intercalating chromophores, 4-nitro- and 4-amino 1,8-naphthalimide, conjugated to a diquat derivative by an ‘orthogonal’ phenyl spacer have been prepared and characterised. ...
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(Blackwell, 2007)Many theoretical models of transition are driven by the assumption that economic decision making is subject to political constraints. In this paper we test whether the 'winners' and 'losers' of economic reform influenced ...
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(Elsevier, 2003-05-02)In humans, thromboxane (TX) A2 signals through two TXA2 receptor (TP) isoforms, termed TPalpha and TPbeta, that diverge exclusively within their carboxyl terminal cytoplasmic domains. The amino terminal extracellular ...