An atom-efficient and stereoselective synthesis has been developed for the preparation of a-2H-labelled(S)-a-amino acids, starting from a novel chiral diketopiperazine scaffold. Efficient mono-alkylation of the chiral ...
Conformationally restricted amino acids are important components in peptidomimetics and drug design. Herein, we describe the synthesis of a novel, non-proteinogenic constrained delta amino acid containing a cyclobutane ...
Fluorinated amino acids are used as enzyme inhibitors, mechanistic probes and in the production of pharmacologically active peptides. Because enantiomerically pure 4-fluoroglutamate is difficult to prepare, the selective ...
A new practical and efficient synthesis of alpha-keto acids was accomplished starting from the synthon 1,4-diacetylpiperazine-2,5-dione. The synthesis encompasses both aromatic and aliphatic substrates proving to be versatile ...
This work has studied a range of acidic catalysts which have been prepared through the modification of mesoporous silica materials. Specifically we have prepared –SO3H modified materials (in the presence and absence of a ...
Odour control from pig production facilities is a significant concern due to increased public awareness and the development of more stringent legislation to control production. Although many technologies exist, biofiltration ...
Sodium caprate (C10) is an oral absorption promoter that is currently in clinical trials as a component of solid dosage forms for poorly permeable small molecules and peptides. Clinical data with zoledronic acid tablets ...
In this paper, statistics-based experimental design with response surface methodology (RSM) was employed to investigate the effect of operation conditions on photoelectrocatalytic oxidation of fulvic acid (FA) using a ...
The photocatalysis of natural organic matter, fulvic acid (FA), by P25 TiO2 in terms of UV254 and TOC concentrations was investigated in this study. The experiments were conducted in a lab-scale photocatalysis-ultrafiltration ...
Concrete is traditionally used as the main component of wastewater facilities. The sulfate and acidic environment presents significant challenges. Supplementary cementitious materials (SCM) such as GGBS are being used in ...