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Browsing by Subject "Valproic acid"

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Class I histone deacetylase inhibition ameliorates social cognition and cell adhesion molecule plasticity deficits in a rodent model of autism spectrum disorder

Foley, Andrew G. ; Gannon, Shane ; Rombach-Mullan, Nanette ; Prendergast, Alison ; Barry, Claire ; Cassidy, Andrew W. ; Regan, Ciaran M. (Elsevier, 2012-09)

In utero exposure of rodents to valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, has been proposed to induce an adult phenotype with behavioural characteristics reminiscent of those observed in autism spectrum ...

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