Browsing by Subject "Oct-1"

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Regulation of the human prostacyclin receptor gene in megakaryocytes : major roles for C/EBPδ and PU.1

Keating, Garret L. ; Turner, Elizebeth C. ; Kinsella, B. Therese (Elsevier, 2012-05)

The prostanoid prostacyclin plays a central role in haemostasis and vascular repair. Recent studies investigating the regulation of the human prostacyclin receptor (hIP) gene identified an upstream repressor region (URR) ...
Transcriptional regulation of the human prostacyclin receptor gene is dependent on Sp1, PU.1 and Oct-1 in megakaryocytes and endothelial cells

Turner, Elizebeth C. ; Kinsella, B. Therese (Elsevier, 2009-02-27)

Prostacyclin plays a central role in haemostasis, inflammation and nociception. However, the factors regulating expression of the prostacyclin receptor (IP) gene in humans, or in other species, have not been identified. ...

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