You are here:
Research Repository UCD
>
Browsing by Subject

Browsing by Subject "Proteins--Structure"

Now showing items 1-5 of 5

Ab initio and homology based prediction of protein domains by recursive neural networks

Walsh, Ian ; Martin, Alberto J. M. ; Mooney, Catherine ; Rubagotti, Enrico ; Vullo, Alessandro ; Pollastri, Gianluca (BioMed Central, 2009-06-26)

Background: Proteins, especially larger ones, are often composed of individual evolutionary units, domains, which have their own function and structural fold. Predicting domains is an important intermediate step in protein ...
Ab initio and template-based prediction of multi-class distance maps by two-dimensional recursive neural networks

Walsh, Ian ; Baù, Davide ; Martin, Alberto J. M. ; Mooney, Catherine ; Vullo, Alessandro ; Pollastri, Gianluca (BioMed Central, 2009-01-30)

Background: Prediction of protein structures from their sequences is still one of the open grand challenges of computational biology. Some approaches to protein structure prediction, especially ab initio ones, rely to some ...
Accurate prediction of protein secondary structure and solvent accessibility by consensus combiners of sequence and structure information

Pollastri, Gianluca ; Martin, Alberto J. M. ; Mooney, Catherine ; Vullo, Alessandro (BioMed Central, 2007-06-14)

Background : Structural properties of proteins such as secondary structure and solvent accessibility contribute to three-dimensional structure prediction, not only in the ab initio case but also when homology information ...
Prediction of short linear protein binding regions

Mooney, Catherine ; Pollastri, Gianluca ; Shields, Denis C. ; Haslam, Niall J. (Elsevier, 2012-01-06)

Short linear motifs in proteins (typically 3–12 residues in length) play key roles in protein–protein interactions by frequently binding specifically to peptide binding domains within interacting proteins. Their tendency ...
Protein structural motif prediction in multidimensional φ-ψ space leads to improved secondary structure prediction

Mooney, Catherine ; Vullo, Alessandro ; Pollastri, Gianluca (Mary Ann Liebert, 2006-10-24)

A significant step towards establishing the structure and function of a protein is the prediction of the local conformation of the polypeptide chain. In this article, we present systems for the prediction of three new ...