Browsing by Subject "Phase-transfer catalysts"

Now showing items 1-2 of 2

From amines to diketopiperazines: a one-pot approach

O'Reilly, Elaine ; Pes, Lara ; Paradisi, Francesca (Elsevier, 2010-03-31)

An efficient one-pot synthesis is described for the preparation of 1,4-disubstituted piperazine-2,5-diones starting from a suitable amine and chloroacetyl chloride in the presence of an aqueous base. The resulting chlo ...
One-step diketopiperazine synthesis using phase transfer catalysis

O'Reilly, Elaine ; Lestini, Elena ; Balducci, Daniele ; Paradisi, Francesca (Elsevier, 2009-04-15)

A simple and efficient one-step procedure is described for the synthesis of a number of symmetrical 1,4-disubstituted piperazine-2,5-diones under phase transfer conditions. The reactions are carried out at room temperature, ...