Browsing by Subject "Amino acids"

Now showing items 1-2 of 2

Bacterial defluorination of 4-fluoroglutamic acid

Donnelly, Clár ; Murphy, Cormac D. (Springer, 2007)

Fluorinated amino acids are used as enzyme inhibitors, mechanistic probes and in the production of pharmacologically active peptides. Because enantiomerically pure 4-fluoroglutamate is difficult to prepare, the selective ...
Mechanism of the binding of Z-L-tryptophan and Z-L-phenylalanine to thermolysin and stromelysin-1 in aqueous solutions

Ceruso, Mariangela ; Howe, Nicole ; Malthouse, J.Paul G. (Elsevier B.V., 2012-02)

The chemical shift of the carboxylate carbon of Z-tryptophan is increased from 179.85 to 182.82 ppm and 182.87 on binding to thermolysin and stromelysin-1 respectively. The chemical shift of Z-phenylalanine is also increased ...