Browsing by Author "Spink, Edward"

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pH stability of the stromelysin-1 catalytic domain and its mechanism of interaction with a glyoxal inhibitor

Howe, Nicole ; Ceruso, Mariangela ; Spink, Edward ; Malthouse, J.Paul G. (Elsevier, 2011-10)

The Stromelysin-1 catalytic domain83-247 (SCD) is stable for at least 16 hours at pHs 6.0-8.4. At pHs 5.0 and 9.0 there is exponential irreversible denaturation with half lives of 38 and 68 min respectively. At pHs 4.5 ...

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